Sisebenzisa iikuki ukuphucula amava akho.Ngokuqhubeka nokukhangela le webhusayithi, uyavumelana nokusetyenziswa kwethu kweekuki.Iinkcukacha ezithe xaxe.
Isiphumo sovavanyo oluchanekileyo sixhomekeke kwingqibelelo yephepha lovavanyo lomchamo.Kungakhathaliseki ukuba yiyiphi i-brand, ukuphathwa ngokungafanelekanga kwemichilo kunokukhokelela kwiziphumo eziphosakeleyo, ezinokuthi zibangele ukuxilongwa kakubi.Ibhotile ye-peel eqiniweyo ngokungafanelekanga okanye i-recapped ibeka umxholo kwindawo efumileyo emoyeni wangaphakathi, onokuchaphazela ingqibelelo ye-peel, ibangele ukuthotywa kwe-reagent, kwaye ekugqibeleni ikhokelela kwiziphumo eziphosakeleyo.
UCrolla et al.1 uqhube uphando apho imicu yovavanyo yavezwa emoyeni wangaphakathi, kwaye izixhobo kunye nemicu ye-reagent yabakhiqizi abathathu bathelekiswa.Isitya somtya kufuneka sitywinwe ngokweengcebiso zomenzi emva kokusetyenziswa, ngaphandle koko kuya kubangela ukubonakaliswa komoya wangaphakathi.Eli nqaku libika iziphumo zophando, ngokuthelekisa i-MULTISTIX® 10SG yokuvavanya umchamo kunye ne-Siemens CLINTEK Status®+ analyzer kunye neemveliso ezivela kwabanye abavelisi ababini.
Iintambo ze-Siemens MULTISTIX® ze-reagent yomchamo (Umfanekiso 1) unebhendi entsha yokuchonga (ID).Xa idityaniswe ne-CLINITEK Status range⒜ umchamo chemistry analyzer eboniswe kumzobo, uthotho lwe-automatic quality checks (Auto-Checks) 2.
Umzobo 2. I-CLINITEK I-Status series analyzers isebenzisa i-algorithm yokufumanisa imicu ye-reagent eyonakaliswe ngumswakama ukuze incede ukuqinisekisa iziphumo zekhwalithi.
Krolla et al.Uphononongo luvavanye iziphumo eziveliswe yindibaniselwano yemigca yovavanyo kunye nabahlalutyi abavela kubavelisi abathathu:
Kumenzi ngamnye, iiseti ezimbini ze-reagent strips zilungiselelwe.Iqela lokuqala leebhotile zavulwa kwaye zavezwa kumoya wangaphakathi (22oC ukuya kwi-26oC) kunye nomswakama wangaphakathi (26% ukuya kuma-56%) ngaphezu kweentsuku ezingama-40.Oku kwenziwa ukulinganisa ukuvezwa ukuba umcu we-reagent unokuvezwa kuwo xa umqhubi engasivali kakuhle isikhongozeli somcu we-reagent (umcu woxinzelelo).Kwiqela lesibini, ibhotile yayigcinwe ivalwe kwaze kwaba yilapho isampuli yomchamo ivavanywa (akukho bar yoxinzelelo).
Malunga nama-200 eesampuli zomchamo zesigulana ziye zavavanywa kuzo zontathu indibaniselwano yebrendi.Iimpazamo okanye umthamo ongonelanga ngexesha lovavanyo kuya kubangela ukuba isampuli yahluke kancinane.Itotali yenani leisampulu ezivavanyiweyo ngumvelisi zichazwe kwiTheyibhile 1. Uvavanyo lwe-Reagent strip lwenziwa kolu hlalutyi lunikiweyo kusetyenziswa iisampulu zesigulana:
Uvavanyo lwesampulu yomchamo lugqitywe kwiinyanga ezintathu.Kwiseti nganye yemicu, egxininisiweyo kwaye ingagxininisi, iisampuli zovavanyo ziyaphindwa kuzo zonke iinkqubo zesixhobo.Kwindibaniselwano nganye yoluhlu kunye ne-analyzer, qhuba ezi sampuli ziphindaphindayo ngokuqhubekayo.
Iziko lonyango lwezigulana ezingalaliswayo elikwindawo yasedolophini yindawo yophando.Uninzi lweemvavanyo lwenziwa ngabancedisi bezonyango kunye nabasebenzi abongikazi, kwaye iimvavanyo zangaphakathi zenziwa ngabasebenzi abaqeqeshiweyo basebhubhoratri (ASCP).
Le ndibaniselwano yabaqhubi iphindaphinda iimeko zovavanyo ezichanekileyo kwiziko lonyango.Ngaphambi kokuqokelela idatha, bonke abaqhubi baqeqeshwa kwaye amandla abo ahlolwe kubo bonke abahlalutyi abathathu.
Kuphononongo olwenziwa nguCrolla et al., Ukuhambelana kokusebenza kohlalutyi phakathi kwemigca yereagent engaxininiswanga kunye noxinzelelo lwavandlakanywa ngokujonga ukuphinda okokuqala kwesethi yovavanyo ngalunye, kwaye ke ukuhambelana kwathelekiswa nokungagxininisi (ulawulo) Thelekisa ukuhambelana. phakathi kweziphumo ezifunyenweyo)-Khuphela 1 kwaye Khuphela 2.
Uluhlu lovavanyo lwe-MULTISTIX 10 SG olufundwe yi-CLINITEK Status+ Analyzer yenzelwe ukubuyisela iflegi yempazamo endaweni yesiphumo esiyinyani ngokukhawuleza ukuba inkqubo ifumanisa ukuba umtya wovavanyo unokuchaphazeleka ngokugqithisileyo kukufuma kokusingqongileyo.
Xa uvavanya kwi-CLINITEK Status + Analyzer, ngaphezu kwe-95% (i-95% yexesha lokuzithemba: 95.9% ukuya kwi-99.7%) ye-MULTISTIX 10 SG egxininisiweyo yokuvavanya ibuyisela iflegi yephutha, ebonisa ngokuchanekileyo ukuba imicu yokuvavanya ichaphazelekile kwaye ngoko ayithinteki. ilungele ukusetyenziswa (Itheyibhile 1).
Itheyibhile 1. Impazamo yokumakisha iziphumo zemicu yovavanyo engaxinzelelwanga kwaye icinezelwe (ukufuma okonakaliswe), ehlelwa ngumenzi.
Imvumelwano yepesenti phakathi kokuphindaphinda ezimbini zemigca ye-reagent engenaxinzelelo kuzo zonke izinto ezintathu zabakhiqizi (ezichanekileyo kunye ne-± 1 iseti) kukusebenza kweentambo ezingenaxinzelelo (iimeko zokulawula).Ababhali basebenzise isikali ±1 kuba lo ngumahluko owamkelekileyo oqhelekileyo wephepha lovavanyo lomchamo.
ULuhlu 2 kunye noLuhlu 3 lubonisa iziphumo zesishwankathelo.Ukusebenzisa ukuchaneka okanye isikali se-±1, akukho mahluko ubalulekileyo ekuphindaphindeni okufanayo phakathi kwemicu ye-reagent yabenzi abathathu phantsi kweemeko zoxinzelelo (p> 0.05).
Ngokwereyithi yokuphindaphinda isantya soxinzelelo lwemichilo yabanye abavelisi, kwaphawulwa ukuba ukuphindaphinda kabini kwemichilo ye-reagent strips, kukho imizekelo emibini kuphela eyahlukileyo yokuhambelana kweepesenti.Le mizekelo ibalaselisiwe.
KwiRoche kunye namaqela ovavanyo lokuxilonga, misela isivumelwano sepesenti phakathi kokuphindaphinda kokuqala kwebar egxininisiweyo kunye nokuphindaphinda kokuqala kwebar engagxininisi ukuvavanya ukusebenza komgca wokuvavanya uxinzelelo lwendalo.
Iitheyibhile 4 kunye ne-5 zishwankathela iziphumo zomhlalutyi ngamnye.Ipesenti yemvumelwano yaba bahlalutyi phantsi kweemeko zoxinzelelo ihluke kakhulu kwipesenti yemvumelwano yeemeko zokulawula, kwaye iphawulwe njenge "ibalulekileyo" kwezi tafile (p<0.05).
Ekubeni iimvavanyo zenitrate zibuyisela iziphumo zokubini (ezimbi/ezilungileyo), zithathwa njengabagqatswa bokuhlalutya kusetyenziswa ±1 iseti yekhrayitheriya.Ngokumalunga ne-nitrate, xa kuthelekiswa nokuhambelana kwe-96.5% ukuya kwi-98%, imichilo yovavanyo loxinzelelo lwe-Diagnostic Test Group kunye ne-Roche ine-11.3% kuphela kwi-14.1 phakathi kweziphumo ze-nitrate ezifunyenwe ukuphindaphinda i-1 phantsi kweemeko ezingenaxinzelelo kunye nokuphindaphinda i-1 phantsi kweemeko zoxinzelelo.Imvumelwano ye% yabonwa phakathi kokuphindwa kwemeko engagxininisiyo (ulawulo).
Kwiimpendulo ze-analyte zedijithali okanye ezingekho-binary, i-ketone, i-glucose, i-urobilinogen, kunye neemvavanyo zeseli ezimhlophe zegazi ezenziwa kwi-Roche kunye ne-diagnostic test strips zinepesenti ephezulu yokwahlukana kwimveliso yebhloko echanekileyo phakathi koxinzelelo kunye nemicu yokuhlola engaxinzekanga. .
Xa umgangatho wokuhambelana wandiswa kwiqela le-± 1, ngaphezu kweprotheyini (i-91.5% consistency) kunye neeseli ezimhlophe zegazi (i-79.2% consistency), ukuhlukana kwee-strip test ze-Roche kwancitshiswa kakhulu, kunye namazinga amabini okuhambelana kunye noxinzelelo. ) Kukho izivumelwano ezahlukeneyo kakhulu.
Kwimeko yokuvavanya kwiqela lovavanyo lokuxilonga, ipesenti yokuhambelana kwe-urobilinogen (11.3%), iiseli zegazi ezimhlophe (27.7%), kunye ne-glucose (57.5%) zaqhubeka zinciphisa kakhulu xa kuthelekiswa neemeko zabo ezingenaxinzelelo.
Ngokusekelwe kwidatha efunyenweyo kunye ne-Roche kunye ne-Diagnostic Test reagent strip kunye ne-analyzer indibaniselwano, umahluko omkhulu phakathi kweziphumo ezinganyanzeliswanga kunye noxinzelelo lwabonwa ngenxa yokuvezwa komswakama kunye nomoya wegumbi.Ngoko ke, ngokusekelwe kwiziphumo eziphosakeleyo ezivela kwimicu eveziweyo, ukuxilongwa okungachanekanga kunye nonyango lunokwenzeka.
Indlela yokulumkisa ngokuzenzekelayo kwi-Siemens analyzer ivimbela iziphumo ukuba zixelwe xa ukubonakaliswa komswakama kufunyenwe.Kwisifundo esilawulwayo, i-analyzer inokuthintela iingxelo zobuxoki kwaye ivelise imiyalezo yephutha endaweni yokuvelisa iziphumo.
I-CLINITEK Status + analyzer kunye ne-Siemens MULTISTIX 10 SG imigca yokuhlola umchamo edityaniswe ne-Auto-Checks iteknoloji ikwazi ukubona ngokuzenzekelayo iintambo zovavanyo ezinokuchaphazeleka kukufuma okugqithisileyo.
I-CLINITEK Status + Analyzer ayifumani kuphela imigca yovavanyo ye-MULTISTIX 10 SG echatshazelwa kukufuma okugqithisileyo, kodwa ikwakhusela ukuxelwa kweziphumo ezinokuthi zingachanekanga.
I-Roche kunye ne-Diagnostic Test Group analyzers abanayo inkqubo yokufumanisa ukufuma.Nangona umtya wovavanyo uchaphazeleka kukufuma okugqithisileyo, ezi zixhobo zimbini zixela iziphumo zesampulu yesigulane.Iziphumo ezichazweyo zinokuthi ziphosakele, kuba nakwisampulu yesigulane esifanayo, iziphumo zohlalutyi ziya kuhluka phakathi kokungabonakali (okungagxininisi) kunye nokuvezwa (kugxininiswe) imichilo yovavanyo.
Kuphononongo olwahlukeneyo lwelebhu, uCrolla neqela lakhe baqaphele ukuba ixesha elininzi umnqwazi webhotile yomchamo wawususwe ngokuyinxenye okanye ngokupheleleyo.Uhlalutyo lugxininisa imfuneko yamaqumrhu ovavanyo ukuze iingcebiso zomenzi ngamnye ziphunyezwe ngamandla ukugcina isikhongozeli seteyiphu sigqunyiwe xa itheyiphu ingasuswanga ukuze kuhlalutywe ngakumbi.
Kwiimeko apho kukho abasebenzi abaninzi (okwenza ukuseka ukuthobela kube nzima), kukwaluncedo ukusebenzisa inkqubo ukwazisa umvavanyi womgca ochaphazelekayo ukuze uvavanyo lungenziwa.
Yenziwe ngemathiriyeli eyadalwa kuqala nguLawrence Crolla, uCindy Jiménez, kunye noPallavi Patel abavela kwiSibhedlele soLuntu saseMntla-ntshona eArlington Heights, Illinois.
Isisombululo se-point-of-care senzelwe ukubonelela ngokukhawuleza, ngokukhawuleza kwaye kulula ukuyisebenzisa iimvavanyo zokuxilonga.Ukusuka kwigumbi likaxakeka ukuya kwiofisi kagqirha, izigqibo zolawulo lwezonyango zinokwenziwa ngokukhawuleza, ngaloo ndlela kuphuculwe ukhuseleko lwesigulane, iziphumo zeklinikhi, kunye nokwaneliseka kwesigulane ngokubanzi.
Umgaqo-nkqubo womxholo oxhasiweyo: Amanqaku kunye nomxholo ohambelanayo opapashwe yi-News-Medical.net unokuvela kwimithombo yobudlelwane bethu obukhoyo bezoshishino, ngaphandle kokuba umxholo onjalo wongeza ixabiso kumoya wokuhlela ongundoqo we-News-Medical.Net, oko kukuthi, imfundo kunye nokwazisa website Iindwendwe ezinomdla kuphando lwezonyango, isayensi, izixhobo zonyango kunye nonyango.
Siemens Healthineers Point of Care ukuxilongwa.(2020, Matshi 13).Uphononongo oluthelekisayo lwezihlalutyi zomchamo ezintathu, ezisetyenziselwa ukuvavanya ukukhangela ukufuma okuzenzekelayo kwimicu yokuhlalutya umchamo efundwa sisixhobo.Iindaba-zoNyango.Ibuyiselwe ngoJulayi 13, 2021 ukusuka https://www.news-medical.net/whitepaper/20180123/A-Comparative-Study-of-Three-Urinalysis-Analyzers-for-Evaluation-of-Automated-Humidity-Check- ye -Instrument-Read-Urinalysis-Strips.aspx.
Siemens Healthineers Point of Care ukuxilongwa."Uphononongo oluthelekisayo lwabahlalutyi bomchamo abathathu abasetyenziselwa ukuvavanya ukufuma okuzenzekelayo kuluhlu lokuhlalutya umchamo ngokufunda isixhobo".Iindaba-zoNyango.NgoJulayi 13, 2021. .
Siemens Healthineers Point of Care ukuxilongwa."Uphononongo oluthelekisayo lwabahlalutyi bomchamo abathathu abasetyenziselwa ukuvavanya ukufuma okuzenzekelayo kuluhlu lokuhlalutya umchamo ngokufunda isixhobo".Iindaba-zoNyango.https://www.news-medical.net/whitepaper/20180123/A-Comparative-Study-of-Three-Urinalysis-Analyzers-for-Evaluation-of-Automated-Humidity-Check-for-Instrument-Read-Urinalysis- Uluhlu .aspx.(Ifikelelwe ngoJulayi 13, 2021).
Siemens Healthineers Point of Care ukuxilongwa.2020. Uphononongo oluthelekisayo lwabahlalutyi bomchamo abathathu abasetyenziselwa ukuvavanya ukufuma okuzenzekelayo koluhlu lohlalutyo lomchamo ngesixhobo sokufunda.I-News-Medical, ijongwe nge-13 kaJulayi, ngo-2021, https://www.news-medical.net/whitepaper/20180123/A-Comparative-Study-of-Three-Urinalysis-Analyzers-for-Evaluation-of-Automated- Humidity- Khangela -for-Instrument-Read-Urinalysis-Strips.aspx.
Sebenzisa uvavanyo lwe-HCG lwe-CLINITEST kwi-CLINITEK analyzer ukufezekisa ukusebenza kweklinikhi kunye nemigangatho yovakalelo
Kudliwanondlebe lwethu lwakutsha nje, sincokole noGqr. Shengjia Zhong malunga nophando lwakhe lwamva nje, oluphande ukusetyenziswa kolawulo lwemida ukunqanda ukusasazeka kwe-COVID-19.
Kulo dliwano-ndlebe, i-News-Medical kunye noNjingalwazi u-Emmanuel Stamatakis baxoxe ngeengxaki zempilo ezinxulumene nokungabikho kokulala.
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I-News-Medical.Net ibonelela ngenkonzo yolwazi lwezonyango ngokuhambelana nale migaqo nemiqathango.Nceda uqaphele ukuba ulwazi lwezonyango kule webhusayithi yenzelwe ukuxhasa endaweni yobudlelwane phakathi kwezigulane kunye noogqirha / oogqirha kunye neengcebiso zonyango abanokubonelela.
Ixesha lokuposa: Jul-14-2021